Zeolite Research

A new anti-diarrheic drug for humans has been developed based on the physical and chemical properties of the purified natural clinoptilolite NZ. A series of physical, chemical, technological, pharmacological, microbiological, and clinical studies were successfully conducted to meet the requirements of the Cuban Drug Quality Agency. The most important results concerning the properties and biological mechanism of NZ are decribed in this paper. Antiviral properties of clinoptilolite Antiviral properties of clinoptilolite of this study suggest that there is a therapeutical case for clinoptilolite against the herpes virus. Magdalena Grce, and Kreimir Pavelic Microporous and Mesoporous Materials. Volume 79, Issues 1–3, 1 April 2005, Pages 165–169 Abstract: The aim of this study was to evaluate the antiviral properties of clinoptilolite, a natural non-toxic zeolite. Herein, a fine powder of micronized zeolite (MZ) was obtained by tribomechanical micronization of natural clinoptilolite. Different viral suspensions were treated with MZ in concentrations ranging from 0.5 to 50 mg/ml. The viral proliferation was evaluated by optical microscope as percentage of cytopathic effect (CPE). Human adenovirus 5, herpes simplex virus type 1 (HSV 1) and human enteroviruses (coxsackievirus B5 and echovirus 7) were used in the antiviral assay. Concentrations of 0.5 and 5 mg/ml of MZ induced a very low antiviral effect or the antiviral was not observed at all, while concentrations of 12, 25 and 50 mg/ml of MZ induced a significant inhibitory effect upon viral proliferation. MZ inhibited the viral proliferation of HSV 1, coxsackievirus B5 and echovirus 7 more efficiently than adenovirus 5. The antiviral effect of MZ seems to be non-specific and is more likely based on the incorporation of viral particles into pores of MZ aggregates than ion exchange properties of clinoptilolite. Our preliminary results indicate a possibility of therapeutical application of MZ, either locally (skin) against herpesvirus infections or orally in cases of adenovirus or enterovirus infections. Futhermore, MZ could also be used in purification of drinking water from different viruses. The aim of this study was to evaluate the antiviral properties of clinoptilolite, a natural non-toxic zeolite. Herein, a fine powder of micronized zeolite (MZ) was obtained by tribomechanical micronization of natural clinoptilolite. Different viral suspensions were treated with MZ in concentrations ranging from 0.5 to 50 mg/ml. The viral proliferation was evaluated by optical microscope as percentage of cytopathic effect (CPE). Human adenovirus 5, herpes simplex virus type 1 (HSV 1) and human enteroviruses (coxsackievirus B5 and echovirus 7) were used in the antiviral assay. Concentrations of 0.5 and 5 mg/ml of MZ induced a very low antiviral effect or the antiviral was not observed at all, while concentrations of 12, 25 and 50 mg/ml of MZ induced a significant inhibitory effect upon viral proliferation. MZ inhibited the viral proliferation of HSV 1, coxsackievirus B5 and echovirus 7 more efficiently than adenovirus 5. The antiviral effect of MZ seems to be non-specific and is more likely based on the incorporation of viral particles into pores of MZ aggregates than ion exchange properties of clinoptilolite. Our preliminary results indicate a possibility of therapeutical application of MZ, either locally (skin) against herpesvirus infections or orally in cases of adenovirus or enterovirus infections. Futhermore, MZ could also be used in purification of drinking water from different viruses. Anticancer and antioxidative effects of micronized zeolite clinoptilolite. The anticancer and antioxidative effects of micronized zeolite clinoptilolite showed a reduction in the cancer count. Zarkovic N, Zarkovic K, Kralj M, Borovic S, Sabolovic S, Blazi MP Anticancer Res. 2003 Mar-Apr;23(2B):1589-95.